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Principles of Genetic Code Expansion
Applications of Genetic Code Expansion
Antibody-related Applications of Genetic Code Expansion
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Welcome to Liu Lab !
Recent publications
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Cao, W.
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, Wang, H.
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, Quan, M.
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, ... , Jiang, W. & Liu, T.* (2023). Reversible control of tetrazine bioorthogonal reactivity by naphthotube-mediated host-guest recognition.
Chem.
Wang, Y.
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, Zhang, J.
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, Han, B.
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, ... , Yang, X.* & Liu, T.* (2023). Noncanonical amino acids as doubly bio-orthogonal handles for one-pot preparation of protein multiconjugates.
Nature Communications.
Wu, D.
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, Zhang, Y.
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, Tang Z.
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, Chen X.
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, ... , Liu X.*, Luo X.* & Liu, T.* (2022). Creation of a Yeast Strain with Co-Translationally Acylated Nucleosomes.
Angew. Chem. Int. Ed.
Ling, X. & Liu, T.* (2022). Innovative CRISPR Screening Promotes Drug Target Identification.
ACS Central Science.
Chen, C.
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, Yu, G.
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, Huang, Y.
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, ... , Ye, H.* & Liu, T.* (2021). Genetic-code-expanded cell-based therapy for treating diabetes in mice.
Nature Chemical Biology.
Ling, X.
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, Chang, L.
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, Chen, H., ... & Liu, T.* (2021). Improving the efficiency of CRISPR-Cas12a-based genome editing with site-specific covalent Cas12a-crRNA conjugates.
Molecular Cells.
Cao, W., Qin, X., Wang, Y., Dai, Z., ... & Liu, T.* (2021). A general supramolecular approach to regulate protein functions by cucurbit [7] uril and unnatural amino acid recognition.
Angewandte Chemie International Edition.
Wang, Y., Chen, X., Cai, W., Tan, L., Yu, Y., ... & Liu, T.* (2021). Expanding the structure diversity of protein building blocks with biosynthesized noncanonical amino acids from aromatic thiols.
Angewandte Chemie International Edition.
Hu, L., Qin, X., Huang, Y., ... , & Liu, T.* (2020). Thermophilic Pyrrolysyl-tRNA Synthetase Mutants for Enhanced Mammalian Genetic Code Expansion.
ACS Synthetic Biology.
Ling, X.
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, Xie, B.
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, Gao, X.
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, ..., Li, M.,* & Liu T.* (2020).Improving the efficiency of precise genome editing with site-specific Cas9-oligonucleotide conjugates.
Sciences Advances.
Qin, X., Tang, H., ..., & Liu T.*(2020). An Orthogonal Tyrosyl-tRNA Synthetase/tRNA Pair from a Thermophilic Bacterium for an Expanded Eukaryotic Genetic Code.
Biochemistry.
Huang, Y., & Liu, T.* (2018). Therapeutic applications of genetic code expansion.
Synthetic and Systems Biotechnology
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