1. Transplantation of chemically induced pluripotent stem-cell-derived islets under abdominal anterior rectus sheath in a type Ⅰ diabetes patient. Shusen Wang, Yuanyuan Du, Boya Zhang, Gaofan Meng, Zewen Liu, Soon Yi Liew, Rui Liang, Zhengyuan Zhang, Xiangheng Cai, Shuangshuang Wu, Wei Gao, Dewei Zhuang, Jiaqi Zou, Hui Huang, Mingyang Wang, Xiaofeng Wang, Xuelian Wang, Ting Liang, Tengli Liu, Jiabin Gu, Na Liu, Yanling Wei, Xuejie Ding, Yue Pu, Yixiang Zhan, Yu Luo, Peng Sun, Shuangshuang Xie, Jiuxia Yang, Yiqi Weng, Chunlei Zhou, Zhenglu Wang, Shuang Wang, Hongkui Deng*, Zhongyang Shen*. Cell, 2024, 187 (22), 6152–6164.

2. Gut symbionts alleviate MASH through a secondary bile acid biosynthetic pathway. Qixing Nie, Xi Luo, Kai Wang, Yong Ding, Shumi Jia, Qixiang Zhao,  Meng Li, Jinxin Zhang, Yingying Zhuo, Jun Lin, Chenghao Guo, Zhiwei Zhang, Huiying Liu, Guangyi Zeng, Jie You, Lulu Sun, Hua Lu, Ming Ma, Yanxing Jia*, Ming-Hua Zheng*, Yanli Pang*, Jie Qiao* and Changtao Jiang*. Cell, 2024, 187(11): 2717–2734.e33.

3. Sequential responsive nano-PROTACs for precise intracellular delivery and enhanced degradation efficacy in colorectal cancer therapy. Liuqing Yang, Yang Ye, Jing Zhang, Minghui Li, Long Yang, Xing Wang, Meifang  Chen, Hua Zhang, Bing He, Xueqing Wang, Wenbing Dai*, Yiguang Wang*, Qiang Zhang*. Signal Transduction and Targeted Therapy, 2024, 9 (11), 5237–5249.

4. Catalytic conversion of mixed polyolefins under mild atmospheric pressure. Binzhi Zhao, Hui Tan, Jie Yang, Xiaohui Zhang, Zidi Yu, Hanli Sun, Jialiang Wei, Xinyi Zhao, Yufeng Zhang, Lili Chen, Dali Yang, Jin Deng, Yao Fu, Zheng Huang, Ning Jiao*. The Innovation, 2024, 5 (2).

5. Generation of human expandable limb-bud-like progenitors via chemically induced dedifferentiation. Jialiang Zhu, Xinxing Zhong, Huanjing He, Jingxiao Cao, Zhengyang Zhou, Jiebin Dong, Honggang Li, Anqi Zhang, Yulin Lyu, Cheng Li*, Hongkui Deng*. Cell stem cell, 2024, 31 (12), 1732–1740.e6.

6. Designing artificial fluorescent proteins and biosensors by genetically encoding molecular rotor-based amino acids. Liming Hu, Wenbing Cao, Yihaofan Jiang, Wenkang Cai, Xiaoding Lou*, Tao Liu*. Nature Chemistry, 2024, 16, 1960–1971.

7. Biomimetic synthesis of pallavicinin, neopallavicinin, pallambins A–D, pallaviambins A/B, and pallavicinolides B/C. Lijun Chen, Peng Chen, Xiwu Zhang, Yu Zhang, Yanxing Jia*. Chem, 2024, 10, 2473–2483.

8. Regioselective Synthesis of 4-Functionalized Pyridines. Chao Li, Zixi Yan, Bingding Wang, Jiaxing Li, Weiping Lyu, Zhixing Wang, Ning Jiao*, Song Song*. Chem, 2024, 10, 628–643.

9. Stereocontrolled synthesis of α-3-deoxy-ᴅ-manno-oct-2-ulosonic acid (α-Kdo) glycosides using C3-substituted Kdo donors. Ao Sun, Zipeng Li, Yuchao Wang, Shuai Meng, Xiao Zhang, Xiangbao Meng, Shuchun Li, Zhongtang Li*, Zhongjun Li*. Angew. Chem. Int. Ed., 2024, 63, e202313985.

10. Identification of Key Post-modification Enzymes Involved in the Biosynthesis of Lanostane-type Triterpenoids in the Medicinal Mushroom Antrodia camphorata. Ya-Qun Zhang, Meng Zhang, Zi-Long Wang, Yang-Oujie Bao, Yu-Qi Wang, Yun-Gang Tian, Lei Ye, and Min Ye*. Angew. Chem. Int. Ed., 2024, e202420104.

11. GlutaR: A High-Performance Fluorescent Protein-Based Sensor for Spatiotemporal Monitoring of Glutamine Dynamics In Vivo. Bingjie Liu,†, Zijie Zhao,†, Pengcheng Wang,†, Kamiran Aihemaitia,, Lixin Zhu, Qingpeng Wei, Wenzhe Li, Xia Yuan, Jing Wu, Changtao Jiang, Min Hao* and Jing Wang*. Angew. Chem. Int. Ed., 2024, e202416608.

12. Structural insights into the terpene cyclization domains of two fungal sesterterpene synthases and enzymatic engineering for sesterterpene diversification. Meng Xu#, Houchao Xu#, Zhenyu Lei#, Baiying Xing, Jeroen S. Dickschat*, Donghui Yang*, Ming Ma*. Angew. Chem. Int. Ed., 2024, 63, e202405140.

13. Construct phenylethanoid glycosides harnessing biosynthetic networks, protein engineering and one-pot multienzyme cascades. Mingju Yao#, Haotian Wang#, Zilong Wang, Chenglin Song, Xiaolin Sa, Wei Du, Min Ye, Xue Qiao*. Angew. Chem. Int. Ed., 2024, e202402546.

14. Chemoenzymatic Synthesis of the Cyclopiane Faminly of Diterpenoid Natural Products. Tao Wang, Jiasheng Zou, Kaibiao Wang, Yuanning Liu, Shouqi Zhang, Yao Kong, Zhengren Xu*. Angew. Chem. Int. Ed., 2024, 63, e202419092.

15. Organelle-Level Trafficking and Metabolism Kinetics for Redox-Responsive Paclitaxel Prodrug Nanoparticles Characterized by Experimental and Modeling Analysis. Canyu Yang, Yao Zhao, Yuanyuan Jiao*, Long Yang, Bing He, Wenbing Dai, Hua Zhang, Qiang Zhang, Xueqing Wang*. ACS Nano, 2024, 18(52), 35230–35247.

16. Local and noninvasive glyco-virus checkpoint nanoblockades restrict sialylation for prolonged broad-spectrum epidemic virus therapy. Xiang Zhang, Pengfei Hao, Juan Mo, Peng-Yu Wang, Guoqing Wang, Letian Li, Xiu-Jing Zheng, Xia Yuan, Wenlong Yao, Ningyi Jin, Chang Li*, Xin-Shan Ye*. ACS Nano, 2024, 18, 32910–32923.

17. Nanomedicines Promote Cartilage Regeneration in Osteoarthritis by Synergistically Enhancing Chondrogenesis of Mesenchymal Stem Cells and Regulating Inflammatory Environment. Shi-He Cui#, Yi Yan#, An Lu#, Yun Dou, Zhen-Wen Li, Ze-Hang Zhu, Ming-Ze Du, Yue-Feng Zhu, Xin Chen, Xiangyu Wang, Lin-Xia Jiang, Yujie Shi, Xiaoyan Liu, Yuan-jun Zhu*, Dong Jiang*, and Jian-Cheng Wang*. ACS Nano, 2024; 18(11): 8125–8142.

18. A microfluidic coculture model for mapping signaling perturbations and precise drug screening against macrophage-mediated dynamic myocardial injury. Zhao Gao, Zhiyong Du, Yu Hou, Kun Hua, Pengfei Tu, Xiaoni Ai*, Yong Jiang*. Acta Pharm. Sin. B, 2024, 14(12): 5393–5406

19. Tuning nanoparticle core composition drives orthogonal fluorescence amplification for enhanced tumour imaging. Meijie Pan, Ruiyang Zhao, Chuanxun Fu, Mingmei Tang, Jiayi Zhou, Bin Ma, Jianxiong Liu, Ye Yang, Binlong Chen, Qiang Zhang, Yiguang Wang*. Nat. Commun., 2024, 15, 7824.

20. A co-assembly platform engaging macrophage scavenger receptor A for lysosome-targeting protein degradation. Qian Wang, Xingyue Yang, Ruixin Yuan, Ao Shen, Pushu Wang, Haoting Li, Jun Zhang, Chao Tian, Zhujun Jiang, Wenzhe Li, and Suwei Dong*. Nat. Commun., 2024, 15, 1663.

21. RNA nanotherapeutics with fibrosis over expression and retention for MASH treatment. Xinzhu Shan, Zhiqiang Zhao, Pingping Lai, Yuxiu Liu, Buyao Li, Yubin Ke, Hanqiu Jiang, Yilong Zhou, Wenzhe Li, Qian Wang, Pengxia Qin, Yizhe Xue, Zihan Zhang, Chenlong Wei, Bin Ma, Wei Liu, Cong Luo, Xueguang Lu, Jiaqi Lin, Li Shu, Yin Jie, Xunde Xian, Derfogail Delcassian, Yifan Ge, Lei Miao*. Nat. Commun., 2024, 15, 7263.

22. Functional Aptamers In Vitro Evolution for Intranuclear Blockage of RNA-Protein Interaction. Jun Li, Panzhu Yao, Ke Tang, Xuyang Zhao, Xiyang Liu, Qinguo Liu, Tongxuan Wei, Hong Xuan, Siqi Bian, Ying Guo*, Zhenjun Yang*, Zhi-Qi Zhang*, and Liqin Zhang*. J. Am. Chem. Soc., 2024, 146, 24654–24662.

23. AND-Gate Logic Forster Resonance Energy Transfer/Magnetic Resonance Tuning Nanoprobe for Programmable Antitumor Immunity Imaging. Xianbin Ma, Mingchuan Mao, Zhenya Liu, Chao Liang, Jiaqi He, Yun Qu, Luzheng Xu, Ran Cheng, Wanru Zhuang, Yao Lei, Weidong Nie, Lan Yuan, Dai-Wen Pang*,Hai-Yan Xie*. J. Am. Chem. Soc., 2024, 146, 31873–31884.

24. Single-Vesicle Electrochemistry in Fresh Brain Slices Enables In Situ Quantification of Vesicular Monoamine. Yuying Liu, Lijiao Cao, Junlan Zhou, Chuqi Li, Jinchang Du, Yifei Xue, Xianchan Li* and Lanqun Mao. J. Am. Chem. Soc., 2025, 147, 149–160.

25. Enantioselective Divergent Syntheses of Diterpenoid Pyrones. Yunpeng Ji, Yaqian Liu, Weiqiang Guan, Chuning Guo, Hongli Jia, Benke Hong, Houhua Li*. J. Am. Chem. Soc., 2024, 146, 9395−9403.

26. Unnatural Amino Acid-Based Ionic Liquid Enables Oral Treatment of Nonsense Mutation Disease in Mice. Yujie Shi *, Ningning Shi, Yuelin Yang, Zhetao Zheng, and Qing Xia*. Adv. Sci., 2024, 11, 2306792.

27. Targeting SLITRK4 Restrains Proliferation and Liver Metastasis in Colorectal Cancer via Regulating PI3K/AKT/NFκB Pathway and Tumor-Associated Macrophage. Xiaojiao Sun , Junling Zhang, Bingqi Dong, Qingqing Xiong, Xin Wang, Yanlun Gu, Zhiqi Wang, Huiyu Liu, Jixin Zhang, Xu He, Hongjin Liu, Yi Zhong, Chuxiao Yi, Xiaowei Chi, Zhenming Liu*, Xiaocong Pang*, Yimin Cui*. Adv. Sci., 2025, 12(1), e2400367

28. A Novel Ubiquitin Ligase Adaptor PTPRN Suppresses Seizure Susceptibility through Endocytosis of NaV1.2 Sodium Channels. Yifan Wang, Hui Yang, Na Li, Lili Wang, Chang Guo, Weining Ma, Shiqi Liu, Chao Peng, Jiexin Chen, Huifang Song, Hedan Chen, Xinyue Ma, Jingyun Yi, Jingjing Lian, Weikaixin Kong, Jie Dong, Xinyu Tu, Mala Shah, Xin Tian*, Zhuo Huang*. Adv. Sci., 2024, 11(29), e2400560.

29. Gene engineered exosome reverses T cell exhaustion in cancer immunotherapy. Peishan Li, Ying Xie, Jinling Wang, Chunjie Bao, Jialun Duan, Yixuan Liu, Qian Luo, Jiarui Xu, Yuxin Ren, Min Jiang, Jianwei Li, Haitao Guo, Huihui Zhao, Guiling Wang, Yanqin Liang*, Wanliang Lu*. Bioact. Mater., 2024, 34, 466–481.

30. Bis-2’-F-cGSASMP isomers encapsulated in cytidinyl/cationic lipids act as potent in situ autologous tumor vaccines. Jing Yu, Xiaotong Yu, Xudong Sun, Quanxin Wang, Sijie Long, Runan Ren, Zhu Guan, Zhenjun Yang*. Mol. Ther., 2024, 32, 1917–1933.

31. Development of miRNA-based PROTACs Targeting Lin28 for Breast Cancer Therapy. ianfei Xu, Xiaoran Zhao, Xingxing Liang, Dongyang Guo, Jing Wang, Qian Wang*, Xinjing Tang*. Sci. Adv., 2024, 10, eadp0334.